MUDr. Ondřej Gojiš, PhD.
Doctor – gynaecology, urogynaecology
Education
2006 MUDr., Third Faculty of Medicine, Charles University, Prague
2013 Ph.D., Third Faculty of Medicine, Charles University, field: Cell biology and pathology
2014 European specialisation in gynaecology and obstetrics
2017 Additional specialisation in urogynaecology
2017 Functional Specialisation F016 – Clinical Nutrition – Society of Clinical Nutrition and Intensive Metabolic Care
Professional experience
2000Laboratories Euro-serum, Port s. Saone, France
2003Department of Plastic and Reconstructive Surgery, Faculty of Medicine, University of Coimbra, Portugal
2002–2003As part of the European Erasmus programme – a one-year fellowship at the Faculty of Medicine, University of Coimbra, Portugal
2005 Department of Plastic Surgery, University Hospital, Linköping, Sweden
2006–2008Department of Surgery, University Hospital Královské Vinohrady, Third Faculty of Medicine, Charles University, Prague
2008–2010Department of Cancer Surgery and Gynaecological Oncology, Imperial College London, Charing Cross Hospital, United Kingdom; Department of Cancer Medicine, Imperial College London – Division of surgical oncology, breast unit. – consultant surgeon Dr. K. Hogben; Department of Gynaecology and Obstetrics: Onco-gynaecological surgery – consultant gynaecological surgeon Dr J.R. Smith
2010–2015ObGyn Clinic, Third Faculty of Medicine, Charles University, University Hospital Královské Vinohrady, Prague
2010 to date Ambicare Clinic, Prague
2015Institute for Mother and Child Care, Podolí, Prague 4
Academic experience
2007–2008Teaching undergraduate students. Third Faculty of Medicine, Charles University – Department of Histology and Embryology
2009 to date author of more than 20 professional articles published in impact journals (Nature, Lancet, British Journal of Cancer, Journal of Clinical Oncology, etc.)
2009 to datemore than 250 citations in international impact journals
2010 to dateassistant professor, ObGyn Clinic, University Hospital Královské Vinohrady, Third Faculty of Medicine, Charles University
2010 to date regular lectures – conference of the Czech Gynaecological and Obstetrical Society
2010 to dateThird Faculty of Medicine, Charles University – assistant professor – Gynaecology Clinic, University Hospital Královské Vinohrady
Research
2006–2013Ph.D. study programme – Third Faculty of Medicine, Charles University in Prague, Department of Pathology, supervisor: Prof. MUDr. Václav Mandys, CSc. Thesis: The role of selected markers in biological behaviour of human breast cancer
2008–2010Department of Cancer Surgery – Imperial College London – S.O.R.A – Dept. of Surgery, Oncology, Reproductive Biology and Anaesthetics – Division of Cancer Medicine: research on the biological behaviour of primary breast cancer tumour cells. Research team leaders: Prof. Carlo Palmieri, Prof. Charles Coombes
Membership
- Czech Gynaecology and Obstetrics Society of the Czech Medical Society of Jan Evangelista Purkyně (Section of Urogynaecology; Section of Infectious Diseases in Gynaecology and Obstetrics; Section of Colposcopy and Cervical Pathology)
- Czech Society of Urogynaecology
Grants and awards
- 2008 European Society for Surgical Oncology (ESSO) – Major Award – the main award for young doctors in the field of cancer surgery.
- 2008 European Society for Medical Oncology (ESMO) – award for young doctors engaged in research and therapy of cancer diseases – Fellowship Award – Training fellowship.
- 2010/2011 Hradec Králové – 3rd place for the best lecture – ORPHEUS – Organiaation for PhD Education in Biomedicine and Health Sciences in the European System.
- 2010/2011 prize of the Minister of Education of the Czech Republic – excellent academic results – based on a proposal of the rector of Charles University
- 2014 Holder of a prestigious scientific award awarded by the Office of the Government of the Czech Republic: Czech Intellect 2014
- 2014 Doctor of the Year 2014
- 2014 Jesenius Prize for Science and Research – awarded to the doctor with the greatest contribution to progress in medicine – Union of Patients and the Czech Medical Chamber
In the media
- FNKV.cz – MUDr. Ondřej Gojiš, Ph.D. received a prestigious scientific award
- Just today – Ondřej Gojiš
- Doctor Vlach Club – This year’s Česká hlava (Czech Intellect) award was also won by one doctor
- J. Hejrovský Institute of Physical Chemistry – Česká Hlava (Czech Intellect) Informs
- Tretiruka.cz – Who are this year’s winners of the Česká Hlava (Czech Intellect) award?
- CZECH INVEST – Six winners received their Česká Hlava (Czech Intellect) award
- Czech Television, Studio 6 – Ondřej Gojiš
- Česká hlava (Czech Intellect) 2014 – Award ceremony for the greatest scientific achievements and research(9:45 a.m. – 3:46 p.m.)
- Psychosomatics and prevention in gynaecology – interview with MUDr. Ondřej Gojiš, Ph.D.
Publishing activities
- SRC3 Phosphorylation at Serine 543 Is a Positive Independent Prognostic Factor in ER-Positive Breast Cancer.
- Zwart W, Flach KD, Rudraraju B, Abdel-Fatah TM, Gojis O, Canisius S, Moore D, Nevedomskaya E, Opdam M, Droog M, Hofland I, Chan S, Shaw J, Ellis IO, Coombes RC, Carroll JS, Ali S, Palmieri C.
Clin Cancer Res. 2015 Sep 14. [Epub ahead of print] - Neoadjuvant chemotherapy and trastuzumab versus neoadjuvant chemotherapy followed by post-operative trastuzumab for patients with HER2-positive breast cancer.
- Palmieri C, Macpherson IR, Yan K, Ades F, Riddle P, Ahmed R, Owadally W, Stanley B, Shah D, Gojis O, Januszewski A, Lewanski C, Asher R, Lythgoe D, de Azambuja E, Beresford M, Howell SJ.
Oncotarget. 2015 Aug 21. [Epub ahead of print] - Expression of selected proteins in breast cancer brain metastases.
- Gojis O, Kubecova M, Rosina J, Vranova J, Celko M, Frajerova D, Zmrhal J, Zahumensky J, Bacova T, Baca V, Mandys V, Kucera E.
Folia Histochem Cytobiol. 2013;51(3):213-8. doi: 10.5603/FHC.2013.0030. - The injury of bladder without penetrate during the TVT surgery for stress incontinence.
- Popelka J, Zmrhal J, Gojiš O.
Ceska Gynekol. 2013 Aug;78(4):356-9. Czech. - Cooperation between mammologist and radiodiagnostic in the management of mammary lesions in the University Hospital Kralovské Vinohrady.
- Bendová M, Malina R, Gojiš O, Večeřová L, Zemanová G.
Ceska Gynekol. 2013 Aug;78(4):333-7. Review. Czech. - Velamentous insertion of the umbilical cord of twin B as a cause of vasa previa in monochorionic diamniotic twins.
- Zahumensky J, Gojis O, Kiss I, Kucera E.
Int J Gynaecol Obstet. 2013 Sep;122(3):261-2. doi: 10.1016/j.ijgo.2013.04.011. Epub 2013 Jun 21. No abstract available. - Expression of steroid receptor coactivator 3 in ovarian epithelial cancer is a poor prognostic factor and a marker for platinum resistance.
- Palmieri C, Gojis O, Rudraraju B, Stamp-Vincent C, Wilson D, Langdon S, Gourley C, Faratian D.
Br J Cancer. 2013 May 28;108(10):2039-44. doi: 10.1038/bjc.2013.199. Epub 2013 May 7. - Site-specific CpG methylation in the CCAAT/enhancer binding protein delta (CEBPδ) CpG island in breast cancer is associated with metastatic relapse.
- Palmieri C, Monteverde M, Lattanzio L, Gojis O, Rudraraju B, Fortunato M, Syed N, Thompson A, Garrone O, Merlano M, Lo Nigro C, Crook T.
Br J Cancer. 2012 Aug 7;107(4):732-8. doi: 10.1038/bjc.2012.308. Epub 2012 Jul 10. - Reproductive functions in women after cancer therapy.
- Záhumenský J, Feldmár P, Kučera E, Zmrhal J, Gojiš O, Kosová T, Bendová M, Stejskal D.
Klin Onkol. 2012;25(3):173-7. Review. Czech. - NT5E CpG island methylation is a favourable breast cancer biomarker.
- Lo Nigro C, Monteverde M, Lee S, Lattanzio L, Vivenza D, Comino A, SyedN, McHugh A, Wang H, Proby C, Garrone O, Merlano M, Hatzimichael E, Briasoulis E, Gojis O, Palmieri C, Jordan L, Quinlan P, Thompson A, Crook T.
Br J Cancer. 2012 Jun 26;107(1):75-83. doi: 10.1038/bjc.2012.212. Epub 2012 May 31. - Methylation of the calcium channel regulatory subunit α2δ-3 (CACNA2D3) predicts site-specific relapse in oestrogen receptor-positive primary breast carcinomas.
- Palmieri C, Rudraraju B, Monteverde M, Lattanzio L, Gojis O, Brizio R, Garrone O, Merlano M, Syed N, Lo Nigro C, Crook T.
Br J Cancer. 2012 Jul 10;107(2):375-81. doi: 10.1038/bjc.2012.231. Epub 2012 May 29. - Differential oestrogen receptor binding is associated with clinical outcome in breast cancer.
- Ross-Innes CS, Stark R, Teschendorff AE, Holmes KA, Ali HR, Dunning MJ, Brown GD, Gojis O, Ellis IO, Green AR, Ali S, Chin SF, Palmieri C, Caldas C, Carroll JS.
Nature. 2012 Jan 4;481(7381):389-93. doi: 10.1038/nature10730. - High frequency of complex TP53 mutations in CNS metastases from breast cancer.
- Lo Nigro C, Vivenza D, Monteverde M, Lattanzio L, Gojis O, Garrone O, Comino A, Merlano M, Quinlan PR, Syed N, Purdie CA, Thompson A, Palmieri C, Crook T.
Br J Cancer. 2012 Jan 17;106(2):397-404. doi: 10.1038/bjc.2011.464. Epub 2011 Dec 20. - Human epidermal growth factor receptor 2-positive breast cancer relapsing post-adjuvant trastuzumab: pattern of recurrence, treatment and outcome.
- Krell J, James CR, Shah D, Gojis O, Lim A, Riddle P, Ahmad R, Makris A, Cowdray A, Chow A, Babayev T, Madden P, Leonard R, Cleator S, Palmieri C.
Clin Breast Cancer. 2011 Jun;11(3):153-60. doi: 10.1016/j.clbc.2011.03.012. Epub 2011 Apr 20. - Management and outcome of HER2-positive early breast cancer treated with or without trastuzumab in the adjuvant trastuzumab era.
- Palmieri C, Shah D, Krell J, Gojis O, Hogben K, Riddle P, Ahmad R, Tat T, Fox K, Porter A, Mahmoud S, Kirschke S, Shousha S, Gudi M, Coombes RC, Leonard R, Cleator S.
Clin Breast Cancer. 2011 Apr;11(2):93-102. doi: 10.1016/j.clbc.2011.03.001. Epub 2011 Apr 11. - The role of SRC-3 in human breast cancer.
- Gojis O, Rudraraju B, Gudi M, Hogben K, Sousha S, Coombes RC, Cleator S, Palmieri C.
Nat Rev Clin Oncol. 2010 Feb;7(2):83-9. doi: 10.1038/nrclinonc.2009.219. Epub 2009 Dec 22. Review. Erratum in: Nat Rev Clin Oncol. 2010 Mar;7(3):122. Coombes, Charles R [corrected to Coombes, R Charles]. - Poor reception?
- Alifrangis C, Harcourt JP, Gojis O, Palmieri C.
Lancet. 2009 Sep 12;374(9693):948. doi: 10.1016/S0140-6736(09)61120-X. No abstract available. - An unusual triple-negative breast carcinoma.
- Shousha S, Peston D, Gojis O, Palmieri C.
Histopathology. 2009 Sep;55(3):364-6. doi: 10.1111/j.1365-2559.2009.03349.x. No abstract available. - The role of steroid receptor coactivator-3 (SRC-3) in human malignant disease.
- Gojis O, Rudraraju B, Alifrangis C, Krell J, Libalova P, Palmieri C.
Eur J Surg Oncol. 2010 Mar;36(3):224-9. doi: 10.1016/j.ejso.2009.08.002. Epub 2009 Aug 28. Review. - FoxM1 is a downstream target and marker of HER2 overexpression in breast cancer.
- Francis RE, Myatt SS, Krol J, Hartman J, Peck B, McGovern UB, Wang J, Guest SK, Filipovic A, Gojis O, Palmieri C, Peston D, Shousha S, Yu Q, Sicinski P, Coombes RC, Lam EW.
Int J Oncol. 2009 Jul;35(1):57-68. - Does ER-betacx really have no clinical importance in tamoxifen-treated breast cancer patients?
- Palmieri C, Gojis O, Rudraraju B, Cleator S.
J Clin Oncol. 2008 Dec 10;26(35):5824; author reply 5825-6. doi: 10.1200/JCO.2008.19.5529. Epub 2008 Nov 10. No abstract available. - Guided tissue regeneration, barrier membranes and reconstruction of the cleft maxillary alveolus.
- Duskova M, Leamerova E, Sosna B, Gojis O.
J Craniofac Surg. 2006 Nov;17(6):1153-60. - Reconstruction of maxilla alveolus for application of dental implant in patients with cleft defect.
- Dusková M, Koťová M, Urban F, Sosna B, Jirkalová R, Strnadel T, Kristen M, Leamerová E, Gojis O.
Acta Chir Plast. 2004;46(4):115-21.
Publication abstracts
- The Role of Steroid Sulfatase in Regulating Stromal-Epithelial Interactions in the Breast and Prostate.
Endocrinology and Metabolic Medicine and Sterix Ltd, Imperial College London, St Mary’s Hospital, London W2 1NY, UK; Cancer Research UK Laboratories, Imperial College London, Hammersmith A. Purohit, H. J. Tutill, J. M. Day, O. Gojis, C. Palmieri and M. J. Reed: Hospital, London W12 0NN, UK. The endocrine society annual meeting, 2009, USA.
Posters
- Phan, Shousha, Gojis: CD10- an important marker in the profiling of triple negative breast cancer. 22nd European Congress of Pathology – European Society of Pathology,2009, Florence, Italy.
- Shah, Gojis, Krell, Ahmad, Riddle, Coombes, Leonard, Fox, Cleator, Palmieri: Management and outcome of HER2-positive breast cancer treated with and without adjuvant trastuzumab: The Imperial College London experience. J Clin Oncol 28:7s, 2010 (suppl; abstr 650). ASCO 2010
- Marla, Cardale, Dodwell, Skene, Gojis, Palmieri, Abram, Cleator, Bowman, Doughty: HER2-positive early breast cancers: What proportion are receiving adjuvant trastuzumab therapy? A multicenter audit. J Clin Oncol 28:7s, 2010 (suppl; abstr 668) ASCO 2010
- Alifrangis, Shipway, Gojis, Emson, Mackie, Coombes, Palmieri: A phase II cross-over study of docetaxel versus vinorelbine in anthracycline-resistant, advanced breast cancer. J Clin Oncol 28:7s, 2010 (suppl; abstr 1097). ASCO 2010
Congresses
- 2008 Oncology Symposium – Cambridge 2008: management of patients with breast cancer – active contribution – chronic pain therapy (Master class of oncology – Breast cancer management)
- 2010 European Society for Surgical Oncology (ESSO) Congress, Bordeaux 2010: O.Gojis: The role of AIB1 in human breast cancer.
- 2010 International Postgraduate Conference Hradec Králové 2010: O.Gojis: The role of AIB1 in human breast cancer.
- 2011 Czech Gynaecological and Obstetrical Society Conference – section Infections in gynaecology and obstetrics – 4 conferences, Prague, lecture: HPV infection during pregnancy (Gojiš, Záhumenský)
- 2011 Kaňka’s Oncology Day
- 2012 National Conference of the Czech Gynaecological and Obstetrical Society – Brno
- 2013 Gynaecological Urology Conference, Nové Zámky, Slovakia: What do we know about the urethra?
- 2013 Urogynaecology Society Conference – What do we know about the urethra?
- 2014 National conference of the Czech Gynaecological and Obstetrical Society, Brno: poster section: The role of tumour markers in breast cancer oncogenesis
- 2015 National Conference of the Czech Urogynaecology Society: Surgical treatment of pelvic organ descent using “single incision” anchored implants – analysis of prospective data.
